Guests 134 Guests
- Conan O'Brien Comedian
- Edna O'Brien Author
- Glenn O'Brien Editorial Director, Interview
- Jack O'Brien Director
- John O'Brien U.S. Army Lt. Colonel (Ret.)
- Miles O'Brien Guest Host
- Timothy O'Brien Journalist, The New York Times, International Herald Tribune
- Brian O'Byrne Actor
- David M. O'Connell President, The Catholic University of America
- Patricia Hitchcock O'Connell Daughter of Alfred Hitchcock
- Patrick O'Connell Grand Chef, Relais & Châteaux
- Carroll O'Connor Actor; Producer
- Gavin O'Connor Director; Screenwriter
- Ian O'Connor Sports Columnist, New York Daily News
- John Cardinal O'Connor Archbishop; Cardinal
- Rory O'Connor President, Globalvision Corporation
- Sandra Day O'Connor Associate Justice, U.S. Supreme Court
- Lawrence O'Donnell Journalist, MSNBC
- Norah O'Donnell Co-Anchor, Host, "CBS This Morning," CBS News
- Michael O'Donoghue Comedy Writer
- Niall O'Dowd Publisher, Irish Voice
- Paul O'Dwyer New York City Commissioner for the United Nations
- Michael O'Hanlon Senior Fellow, Brookings Institution
- Kelli O'Hara Actor
- Joseph O'Hare Reverend; President, Fordham University
- Ed O'Keefe Congressional Reporter, The Washington Post
- Martin O'Malley Governor of Maryland
- Buck O'Neil Former Baseball Player; Author
- Shannon O'Neil Senior Fellow, Council on Foreign Relations
- Catherine O'Neill Co-Founder, Women's Commission for Refugee Women and Children; Journalist
- Jim O'Neill Former Executive, Goldman Sachs
- Joseph O'Neill Author
- Paul O'Neill U.S. Secretary of the Treasury
- Anthony O'Reilly Former Chairman, Former C.E.O., H.J. Heinz
- Bill O'Reilly Host, Fox News, "The O'Reilly Factor"
- David O'Reilly Chairman and C.E.O., Chevron Texaco Corporation
- Tim O'Reilly C.E.O., Founder, O'Reilly Media
- Meghan O'Rourke Culture Editor, Slate
- P. J. O'Rourke Author; Political Satirist
- P.J. O'Rourke Author; Journalist
- John O'Sullivan Editor, National Review
- Meghan O'Sullivan Senior Fellow and Lecturer, John F. Kennedy School of Government, Harvard University
- Mary Ellen O'Toole Director, GMU Forensic Science Department
- Peter O'Toole Actor
- John Oates Singer-Songwriter
- Joyce Carol Oates Author; Professor, Princeton University
- Barack Obama President, U.S.
- Michelle Obama First Lady of the United States
- Mahdi Obeidi Former Head, Iraqi Centrifuge Program; Former Director-General, Iraq Ministry of Industry and Mining
- Otto Obermaier Former U.S. Attorney, Southern District of New York
- Conor Oberst Singer-songwriter
- Mauricio Obregon Narrator, PBS's "Columbus and the Age of Discovery"; Historian
- Lynda Obst Producer; Author
- Christine Ockrent Journalist; Author
- Ray Odierno General, Chief of Staff, U.S. Army
- William Odom Senior Fellow, Hudson Institute; Ret. Lt. General
- Leslie Odom, Jr. Actor
- Avodah Offit Author; Psychiatrist
- Charles Ogletree Professor, Harvard Law School
- Kongdan Oh Fellow, The Brookings Institution
- Alexis Ohanian Author; Co-Founder, Reddit
- Norio Ohga President and C.E.O., Sony Corporation
- Mirta Ojito Staff Writer, The New York Times
- Emeka Okafor NBA Basketball Player, Charlotte Bobcats
- Daniel Okimoto Political Science Professor, Stanford University
- Sophie Okonedo Actor
- Dan Okrent Managing Editor, Life Magazine
- Michel Oksenberg Senior Fellow, Asia–Pacific Research Center, Stanford University
- Milton Okun Record Producer
- Olafur Olafsson Author; President, Sony Electronic Publishing
- Hakeem Olajuwon Center, Houston Rockets
- Keith Olbermann GQ Special Correspondent
- Gary Oldman Actor
- Sharon Olds Poet
- Thomas Oliphant Journalist, The Boston Globe
- April Oliver TV Producer
- Jamie Oliver Chef; Restaurateur; Author
- John Oliver Comedian
- Kimberly Oliver 2006 National Teacher of the Year; Kindergarten, Broad Acres Elementary School
- L. Jay Olivia President, New York University
- Ehud Olmert Former Prime Minister of Israel
- Edward James Olmos Actor
- Jose Maria Figueres Olsen President, Carbon War Room; Former President, Costa Rica
- Matt Olsen Former director of the National Counterterrorism Center
- Jay Olshansky Professor, University of Illinois
- Lynne Olson Author; Professor, American University
- Mike Olson Musician
- Ted Olson Attorney, Apple; Former Solicitor General
- Michael Ondaatje Author
- Yasuaki Onuma Professor, International Law University of Tokyo
- Niels Arden Oplev Director
- Andres Oppenheimer Journalist, The Miami Herald
- Michael Oppenheimer Director, Earth System Science Center, Penn State University
- Christine Orban Author
- Michael Oren Israeli Ambassador to the United States
- Michael Oreskes Author; Executive Editor, International Herald Tribune
- Deborah Orin Washington Bureau Chief, The New York Post
- Dean Ornish President, Preventive Medical Research Institute
- Norman Ornstein Scholar, American Enterprise Institute
- Bob Orr Homeland Security Correspondent, CBS News